COMBINED 213 nm+1444 nm LASER ABLATION TREATMENT OF BOVINE CORNEA
Abstract
The laser ablation efficiency of eye cornea for UV (213 nm) and combined IR+UV (213 nm + 1444 nm) ablation treatment in safe conditions, preventing laser coagulation at 1444 nm, was investigated. It is shown that the IR+UV combination, when, at the first stage of cornea treatment, an IR laser pulse at 1444 nm, falling into a water absorption band with an absorption coefficient of about 31 cm–1, dehydrates a superficial corneal layer and at the second stage, in about 100 ms, a UV laser pulse at 213 nm ablates a thin (about 1–3 mm) collagen layer, gives promising results. Due to the controlled dehydration of the corneal surface, the process of 213 nm + 1444 nm laser ablation ensures a better reproducibility and a higher productivity.
About the Authors
S. A. Batishche
B. I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus, Minsk
Belarus
Belarus
S. V. Bushuk
B. I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus, Minsk
Belarus
Belarus
A. A. Kouzmouk
B. I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus, Minsk
Belarus
Belarus
A. V. Savitch
B. I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus, Minsk
Belarus
Belarus
H. A. Tatur
B. I. Stepanov Institute of Physics of the National Academy of Sciences of Belarus, Minsk
Belarus
Belarus
G. Grabner
Paracelsus Medical University, University Eye Clinic, Salzburg
Austria
Austria
W. Kautek
University of Vienna, Department of Physical Chemistry, Vienna
Austria
Austria
References
1. Femtosecond-pulse laser ablation of human corneas / W. Kautek [et al.] // Appl. Phys. A. – 1994. – Vol. 58. – P. 513–518.
2. Krüger, J. Ultrashort Pulse Laser Interaction with Dielectrics and Polymers / J. Krüger, W. Kautek // Advances in Polymer Science. – Berlin; Heidelberg: Springer-Verlag,. 2004. – Vol. 168. – P. 247–289.
3. Lubatschowski, H. Ophthalmic Applications / H. Lubatschowski, A Heisterka // Femtosecond Technology for Technical and Medical Applications. Topics in Applied Physics / Eds: F. Dausinger, F. Lichtner, H. Lubatschowski. – Heidelberg: Springer-Verlag, 2004. – Vol. 96. – P. 187–201.
4. Fisher, B. T. Measurement of small-signal absorption coefficient and absorption cross section of collagen for 193-nm excimer laser light and the role of collagen in tissue ablation / B. T. Fisher, D. W. Hahn // Appl. Optics. – 2004. – Vol. 43. – P. 5443–5451.
5. Pettit, G. H. Corneal-tissue absorption coefficients for 193and 213-nm ultraviolet radiation / G. H. Pettit, M. N. Ediger // Appl. Opt. – 1996. – Vol. 35. – P. 3386–3391.
6. UV Solid State Laser (213nm) Photo-Refractive Keratectomy / Q. Ren [et al.] // Ophthalmology. – 1994. – Vol. 101. – P. 883–889.
7. Solid state lasers for ocular surgery: preclinical stud / R. Cubeddu [et al.] // Proc. SPIE. – 1994. – Vol. 2079. – P. 177–182.
8. Comparing 213 nm and combined 213 nm + 1440 nm laser ablation treatment of bovine cornea / S. Batishche [et al.] // Plasma physics and plasma technology: VII Intern. Conf., Minsk, Belarus, Sept. 17–21, 2012. – Minsk, 2012. – Vol. 1. – P. 392–395.
9. Mechanistic comparison of pulse laser induced phase separation of particulates from cellulose paper at 213 nm and 532 nm / S. Arif [et al.] // Appl. Phys. A. – 2013. – Vol. 110. – P. 501–509.
10. A powerful, repetitively pulsed 1444-nm Nd:YAG laser / S. A Batishche [et al.] // Quantum Electronics. – 2000. – Vol. 30. – P. 673–674.
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