SEARCH FOR DRUG-RESISTANCE MUTATIONS IN M. TUBERCULOSIS GENOME SEQUENCES
Abstract
We investigate algorithms for genome-wide association studies. A methodology is proposed that allows searching for drugresistance mutations in mycobacterium tuberculosis whole genomes. We present the experimental results on identification of resistance mutations to major anti-TB agents using patientsʼ data from Belarus.
About the Authors
R. S. Sergeev
United Institute of Informatics Problems of the National Academy of Sciences of Belarus
Belarus
Belarus
I. S. Kavaliou
EPAM Systems
Belarus
Belarus
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